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NIIH | On-Going Projects List

On Going Projects

Sr. No. Title
1 A flow cytometry assay and rapid agglutination test for the detection of anti-FVIII antibodies- SERB
PI: Dr. Rucha Patil
2 Antibody Profile in post- vaccinated individuals when compared to post-COVID-19 patients
PI: Dr. Rucha Patil
3 Clinical, Immunological and Molecular characterization of an Autoimmune Lymphoproliferative Syndrome (ALPS) and B-cell expansion with NF?? and T- cell anergy(BENTA) in Indian population.
PI: Dr. Manisha Madkaikar
4 Clinical, Molecular and Cytogenetic Study of Myeloproliferative neoplasms
PI: Dr. Babu Rao Vundinti
5 Comprehensive immune profiling and its correlation with response to therapy and underlying genetic variations in Immune Thrombocytopenia (ITP).
PI: Dr. Manisha Madkaikar
6 Defining immunological markers for response to therapy in Aplastic Anemia
PI: Dr. Manisha Madkaikar
7 Development of G6PD point of care test (ICMR)
PI: Dr. Rucha Patil
8 Exploring immune players in clinical conditions of HBV infection.
PI: Dr. Anindita Banerjee
9 Exploring lymphocyte subsets and cytokine profile in Pediatric Inflammatory Multisystem Syndrome temporally related to SARS-CoV-2 infection (PIMS-TS). (Intramural)
PI: Dr. Manisha Madkaikar
10 ICMR Task force study on Rational Use of Medicines
PI: Dr. Manisha Madkaikar
11 Identification and molecular characterization of weak D variants among apparently RhD negative individuals from South India (Intramural project in collaboration with JIPMER)
PI: Dr Swati Kulkarni
12 Immune response to precautionary third dose of COVISHIELD/COVAXIN among healthy adult population: an ICMR Cohort study, India
PI: Dr. Reetika Yadav
13 Molecular studies of Keap1-Nrf2 signalling axis in the pathophysiology of Sickle cell disease: an exploratory study
PI: Dr. Naga Merugu
14 Multi Centric Collaborative Study of the National Registry for Rare Disorders in India- Bleeding disorders
PI: Dr. Rucha Patil
15 Platelet phenotyping (surface receptors, granules, secretion, and signal transduction) and genotyping of unclassified heritable thrombocytopenia and platelet function disorders.
PI: Dr. Bipin Kulkarni
16 Role of angiotensin converting enzyme 2 and vitamin D in endothelial dysfunction among COVID-19 patients from Mumbai, Maharashtra
PI: Dr. Vandana Pradhan
17 Role of Ion Channelopathies in Sickle Cell Disease
PI: Dr. Prashant P Warang
18 Strengthening of ICMR-MRUs: Establishment of Autoimmune Diagnostic Laboratories for early detection and management of Autoimmune Disease and empowering MRUs for research in autoimmunity
PI: Dr. Vandana Pradhan
19 Studies on ABO histo?blood group genes and ACE2 as potential genetic susceptibility factors to SARS-CoV-2 infections: an exploratory study
PI: Dr. Swati Kulkarni
20 Studies on the role of CD47/SIRP?-interaction in regulation of erythrophagocytosis
PI: Dr. Naga Merugu
21 Study of DNA methylation of Polycomb genes and micro RNAs in Drug Resistance CML patients
PI: Dr. Babu Rao Vundinti
22 Study of genetic factors and immune parameters focusing on the transmission of HBV in household contacts of classical HBV cases
PI: Dr. Anindita Banerjee
23 Study of genome wide expression profiling of long non coding RNAs (lncRNAs) and mRNA association with myelodysplastic syndromes pathogenesis
PI: Dr. Babu Rao Vundinti
24 Study of micro-RNA expression profile in common variable immunodeficiency disorder
PI: Dr. Manisha Madkaikar
25 Study of molecular pathology of Idiopathic Aplastic Anemia
PI: Dr. Babu Rao Vundinti
26 Study of the molecular mechanism of bone marrow failure and cancer risk in Fanconi anemia complementation groups
PI: Dr. Babu Rao Vundinti
27 Study on Polio and Non-Polio enterovirus infections in children withimmunodeficiency at multiple medical institutes across India. Phase II
PI: Dr. Manisha Madkaikar
28 The role of epigenetic factors in Fanconi anemia phenotype and cancer predisposition
PI: Dr. Babu Rao Vundinti
29 To study the role of mitochondrial DNA damage due to iron overload in transfusion dependent Thalassemia major
PI: Dr. Reetika Yadav
30 To study the role of Regulatory T cells in failure to mount an adequate immune response post-Hepatitis B vaccination
PI: Dr. Reetika Yadav
31 Tranexamic acid combined with recombinant factor VIII for haemophilia patients- (ICMR)
PI: Dr. Rucha Patil
32 Study on Factors Influencing Implementation of Iron and Folic Acid Supplementation in Pregnant Women under Anaemia Mukt Bharat Program
PI: Dr. Amrutha Jose
33 Investigating the role of human gut microbiome in sickle cell disease – (Institutional funding)
PI: Dr. Chhedi Lal Gupta

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