Department of Hemostasis and Thrombosis

 

Name : Dr. Shrimati Dharmapal Shetty

Degree : M.Sc. Ph.D

Designation : Scientist E

Email : shrimatishetty@yahoo.com

 

Education:

  • Ph. D (Applied Biology) from Mumbai University . in July 1997.

Title : Detection of mutants and Mutant carriers in Haemophilia A and B families from India

  • M.Sc (Zoology- Genetics specialization) from Manasagangotri, Mysore University, in 1980, with first class and Distinction ( Second Rank in the University).
  • B.Sc (Botany, Zoology, Chemistry) from St. Agnes College, Mangalore, Mysore University with first class in the year 1978.

Fellowships

  • Haemophilia Federation ( India) & Angelo Bianchi Bonomi Institute of Haemophilia & Thrombosis Center , Milano, Italy sponsored training to study the genetic diagnostic techniques and strategies for haemophilia from Jan – March 1994 ( 3 months)
  • As a Co- Investigator Under the ICMR – INSERM Project entitled “Catalytic antibodies to factor VIII in haemophilia patients – implications for an alternative therapeutic approach” underwent training for 1 month at INSERM, Paris, France from Nov- Dec 2001 (1 month)

Awards/ Honors

  • Young Scientist Award in the year 1997 Indian Society of Haematology & Blood Transfusion for the work on “ Carrier detection and antenatal diagnosis in haemophilia A and B families in Indian population”
  • L. Hiranandani Award for the Best Poster from the Mumbai Haematology Group for the paper entitled “ Comparison of the coagulation paraqmeters with the molecular biology data in the classification of carriers and noncarriers in haemophilia A families” in the year 1998
  • BGRC Silver Jubilee Oration award from Indian Council of Medical Research (ICMR) for the year 2000 for the work on “ Genetics of Haemophilia”
  • Reach the Developing World Grant from International Society of Thrombosis & Haemostasis for the year 2003 and 2007 in their Annual Conferences held at Birmingham, UK and Geneva, Switzerland respectively.
  • Early Career Investigator award from Bayer Health Care, USA as a Principal Investigator in the project entitled “ Thrombohaemorrhagic Balance in Haemophilia – Implications for an alternative therapeutic approach” in the Annual Conference of World Haemophilia Congress held at Bangkok in 2004

Fields of interest: Haemostasis and Thrombosis,Molecular Biology,Platelet Biology

Research Guide

  • Research Guide for M.Sc and Ph.D in Applied Biology - University of Mumbai
  • Research Guide for Ph.D in Medical Biotechnology- West Bengal University of Health Sciences, Kolkata
  • Research Guide for Ph.D in Haematology, Maharashtra University of Health Sciences, Nashik.

Publications:

Chapters in Books/ Monographs: 5

International Journals: 103

National Journals : 24

International abstracts: 40

National abstracts: 60

Latest 10 publications:

  1. Shetty S , Bhave M, Ghosh K. Acquired hemophilia A: Diagnosis, aetiology, clinical spectrum and treatment options. Autoimmun Rev . 2010 Nov 27
  2. Shetty S , Ghosh K. Thrombophilic dimension of Budd chiari syndrome and portal venous thrombosis - A concise review. Thromb Res . 2010 Oct 19.
  3. Ghosh K, Shetty S. Immune response to FVIII in hemophilia A: an overview of risk factors. Clin Rev Allergy Immunol. 2009 Oct;37 (2):58-66.
  4. Shetty S, Kulkarni B, Pai N, Mukundan P, Kasatkar P, Ghosh K. JAK2 mutations across a spectrum of venous thrombosis cases. Am J Clin Pathol . 2010 Jul;134(1):82-5.
  5. Shetty S , Ghosh K. Anti-phospholipid antibodies and other immunological causes of recurrent foetal loss--a review of literature of various therapeutic protocols. Am J Reprod Immunol. 2009 Jul;62(1):9-24.
  6. Shetty S , Vora S, Kulkarni B, Mota L, Ghosh K. Antiphospholipid antibodies in haemophilia patients with severe bleeding tendency: cause, consequence or a consequential cause? Haemophilia. 2009 Sep;15(5):1104-8.
  7. Pai N, Shetty S, Idicula-Thomas S, Kulkarni B, Ghosh K. Hereditary basis of protein C deficiency (PCD) in thrombosis patients: first report from India . Thromb Haemost. 2009 Apr;101(4):785-7.
  8. Shetty S , Ghosh K. Reduced clinical severity in a mutationally well-characterized cohort of severe hemophilia with associated thrombophilia. Am J Clin Pathol. 2008 Jul;130(1):84-7; quiz 146.
  9. Shetty S, Ghosh K, Quadros L. Amelioration of clinical severity of similar mutations severe factor IX deficiency by coinherited thrombophilia. Eur J Haematol. 2008 Jan;80(1):87-9.
  10. Shetty S , Vora S, Kulkarni B, Mota L, Vijapurkar M, Quadros L, Ghosh K. Contribution of natural anticoagulant and fibrinolytic factors in modulating the clinical severity of haemophilia patients. Br J Haematol. 2007 Aug;138(4):541-4.