Department of Hematogenetics

Name : Dr. Ajit C. Gorakshakar

Degree : M.Sc, Ph.D

Designation : Scientist “E”

email :ajit5678@yahoo.com

Education :

Fellowship /Training

a) Indo-French Fellowship: Sponsored by Indo-French Centre for Promotion in Advanced Research, New Delhi for the period of 10 months ( 1993-1994) at INSERM U-120 Hopital Robert Debre, Paris with Dr. R. Krishnamoorthy & Dr. J Elion.

b) Attended a practical course in “Gene expression in mammalian systems” in Nov 1998,organized by International Center for Genetic Engineering and Biotechnology, New Delhi

Prizes, Awards

1. The Dr B.C.Mehta diamond jubilee endowment best paper prize in the “Original Article” section Application of covalent reverse dot blot hybridization for rapid prenatal diagnosis of the common Indian thalassemia syndromes. By Colah RB, Gorakshakar AC, Lu CY, Nadkarni AH, Desai SR, Lulla CP, Krishnamoorthy R, Mohanty D . Ind J. Hematol. Blood Transfu. 15(1):10-13,1997.
2. Best poster award at 40 th Annual Conference of Indian Society of Hematology and Transfusion Medicine held at Pune Dec 1999. “Identification of a rare beta thalassemia mutation codon 121 (G > T ) in a family from Karnataka”. By Gorakshakar AC, Nadkarni A, Phanasgaonkar S, Colah R, Mohanty D.

Field of Interest: Hemoglobinopathies, molecular genetics, population genetics, blood group serology, prenatal diagnosis.

Research Guide: Research Guide for M.Sc & Ph D in Applied Biology - University of Mumbai.

Publications:

Chapter in Books / Monographs - 3

International Journals - 50

National Journals - 46

International/National Abstracts - 23

Research Guide

• University of Mumbai, MSc and Ph.D. in Applied Biology.
• Maharashtra University of Health Sciences for Ph.D. in Hematology and Transfusion Medicine

Latest 10 Publications

1. Colah RB, Gorakshakar A, Nadkarni A : Global burden, distribution and prevention of β-thalassaemia and haemoglobin E disorders. Expert Reviews of Hematology. 3(1) 103-117, 2010.

2. Nadkarni A, Gorakshakar A, Surve R, Sawant P, Phanasgaonkar S, Nair S, Ghosh K, Colah R: Analysis of novel and rare b  Thalassemia mutations among Indians. Hemoglobin 33(1):59-65,2009.

3. Colah R, Gorakshakar A, Nadkarni A, Phansagaonkar S, Surve R, Sawant P, Mohanty D, Ghosh K. Regional heterogeneity of β-thalassemia mutations in the multiethnic Indian population. Blood Cells Molecules & Disease. May- Jun 42(3),241 -246,2009.

4. Ray S, Vasantha K, Ghosh K, Gorakshakar AC. Molecular characterization of ABO blood groups among Indians : the first report. Vox Sang. 97(suppl 1) : 143,2009.

5. Gorakshakar AC, Vasantha K, Ray S, Ghosh K: Molecular characterization of ABO alleles in one tribal population from Western India . Vox Sang 97 (suppl 1) 143,2009.

6. Colah R, Gorakshakar A, Phansagaonkar S, D’souza E, Nadkarni A, Surve R, Sawant P, Master D, Patel R, Ghsoh K, Mohanty D : Epidemiology of β- thalassemia in Western India : mapping the frequencies and mutations in sub-region of Maharashtra and Gujarat . Britt. J. Haematol. Jun 149(5) : 739- 47, 2009.

7. D’Souza E, Sawant P, Nadkarni A, Gorakshakar A, Mohanty D, Ghosh K, Colah R: Evaluation of the use of monoclonal antibodies and nested PCR for non- invasive prenatal diagnosis of hemoglobinopathies in India . Am J Clin Patho 130(2):202-209,2008.

8. Nadkarni A, Wadia M, Gorakshakar AC, Kiyama R, Colah R and Mohanty D: Molecular characterization of db thalassemia and HPFH in the Indian population. Hemoglobin 32(5):425-433,2008.

9. Gorakshakar AC & Ghosh K : National & Ethnic Human Mutation Database : A need of the Day. Ind. J. Hum. Genet. 14(3) : 75-76,2008.

10. Kulkarni S, Gorakshakar A, Colah RB,Gupte SC, Mohanty D : Usefulness of prenatal detection of RhD typing by molecular analysis in Indians. J Postgraduate Med 53(2) : 149 ; 2007.